A rare case of Candida famata associated endometritis in cross bred Jersey cow

Abstract

Endometritis, an inflammation of endometrium, is one of the major causes of reduced reproductive efficiency in bovines Among microbial etiologies of endometritis fungal causes are rarely reported. A 4-year-old, cross bred jersey cow with high fever history and whitish mucopurulent discharge from vulvar opening for 1.5 years was treated with long acting oxytetracycline (intramuscularly) for 3 days with failure to cure. The uterine discharge was collected from the cow and processed for isolation of cauisative agent and further antimicrobial susceptibility testing. Pure yeast like colonies were observed on SDA after 48 hours of incubation at 37^oC. Which was purified and confirmed as Candida famata based on phenotypic characteristics. Antifungal susceptibility testing following disk diffusion method revealed sensitivity of isolate for Fluconazole, Ketoconazole, "Amphotericin-B, Nystatin, Itraconazole and Miconazole but was resistant to Clotrimazole. In conclusion, C. famata was detected as causal agent of endometritis in cow and thus identification of fungal etiologies in antibiotic treatment of unresponsive cases of endometritis is important.